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Gastrointestinal events were the most common adverse effects in both arms and occurred primarily during dose escalation
Randomized clinical study: Partially hydrolyzed guar gum (PHGG) versus placebo in the treatment of patients with irritable bowel syndrome
Mild and temporary side effects may include localized injection site irritation, transient water retention, or changes in appetite
Horowitz M, Flint A, Jones KL, Hindsberger C, Rasmussen MF, Kapitza C, et al
however, evaluation of clinically important primary outcomes has not shown improvement and should be prioritized in future trials
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