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However, current and next-gen obesity therapeutics have the potential to vastly improve health outcomes

By enhancing satiety through increased endogenous GLP-1, CCK, and PYY while reducing ghrelin levels, these polyols may help consumers limit caloric intake and manage their weight more effective 3

Although investigations in animals are scarce, studies among humans have suggested that GLP-1 RAs directly mitigate the development of coronary atherosclerosis through several mechanisms (Table 1)

These improvements reduce the burden associated with frequent injections and make GLP-1 therapies more accessible to a broader population, such as those who may be hesitant about injectable medications

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