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In the emulation of SURPASS-CVOT comparing tirzepatide to dulaglutide in patients at high cardiovascular risk (Table 2 and Supplementary Table 19), the estimated HR was 0.83 (95% CI 0.69 to 1.01) compared to the trial estimates of HR 0.92 (95% CI 0.83 to 1.01)
Some studies (like a recent one tracking over 18,000 adults)suggest that tirzepatide (used in Mounjaro and Zepbound), may lead to slightly more weight loss on average than semaglutide (in Wegovy, Ozempic, and Rybelsus)
Cost Wegovy retail price is ~$1,500 monthly
The analysis indicated no statistically significant age-related differences in serum GR activity among healthy adults
We recommend you to discuss with your healthcare provider before taking any medication or supplements Caution: Consult physician if pregnant/nursing, taking medication, or have a medical condition
