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The effect is dose-dependent each hour of sleep lost compounds the biological cost

Paris 91 (3-5), 173178

Contact your GP or diabetes specialist if blood glucose control is inadequate, you experience significant side effects (particularly persistent gastrointestinal symptoms or severe abdominal pain), develop signs of hypoglycaemia, or have questions about your medication regimen

Finally, there is some clinical evidence suggesting that high doses of carnitine may lower the seizure threshold in susceptible individuals, making medical supervision essential for those with a history of seizure disorders

It is still far more stable than a reconstituted solution, but the seal is broken