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"With more data, we may be able to say that berberine helps decrease the risk of developing Type 2 diabetes." Studies that looked at the effect of berberine in people with type 2 diabetes suggest that berberine has a glucose-lowering effect
10.1016/j.xphs.2016.06.024 19 KerstenS.StienstraR
Supplementation works best when combined with lifestyle interventions that improve insulin sensitivity, such as exercise and weight loss
The honest caveat: this was a retrospective, single-center study helpful and encouraging, but not a randomized controlled trial
Ferroptosis may promote osteoclast bone resorption by inhibiting osteoblast function, thereby affecting the homeostasis and structural integrity of subchondral bone and leading to the occurrence of osteoarthritis (164, 165)
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