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The dependence of tyrosine hydroxylase on BH 4 necessitates the coupling to the action of dihydropteridine reductase (encoded by the QDPR gene: quinoid dihydropteridine reductase) as is the situation for tryptophan hydroxylase (see below) and phenylalanine hydroxylase
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General Deficiency Correction and Hematologic Goals Cyanocobalamin works well for general repletion, especially in cases of dietary deficiency, gastrointestinal malabsorption, or post-surgical needs
& Schlaepfer, I
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