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First is the urate-lowering agents allopurinol and febuxostat, which are traditional clinical agents used to inhibit xanthine oxidase and reduce uric acid levels
This could be the mechanism by which XO inhibitors provide protective effects in ischemia/reperfusion-related conditions (Khatib et al., 2001)
Rosmolen, W
Once-daily upadacitinib versus placebo in adults with extensive non-segmental vitiligo: a phase 2, multicentre, randomised, double-blind, placebo-controlled, dose-ranging study
The lips gradually thin as collagen production decreases, making them more prone to cracking and dryness similar to a balloon that slowly loses air over time
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