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Clinical studies show measurable weight reduction typically within 4-8 weeks of dose escalation
Mild heat rash or friction-related redness may improve with cool compresses, loose clothing, gentle soap, and avoiding heat
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Earlier initiation of SGLT2is or GLP-1RAs may provide cardiometabolic protection before the development of advanced disease, whereas longer-standing disease often necessitates combination therapy due to progressive -cell dysfunction and accumulated risk [8]
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