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In May 2022, Tirzepatide was approved for marketing by the FDA for the treatment of type 2 diabetes in adults
Rossi, R
But these anecdotal reports are not a substitute for a well-powered, randomized double-blind placebo-controlled trial, he points out
A: We prioritize quality and transparency
For tirzepatide (Zepbound) Jastreboff and colleagues reported in the New England Journal of Medicine in 2022 that at maximal doses, the percent of individuals reporting side effects were as follows: Nausea 31.0% Diarrhea 23.0% Vomiting 12.2% Constipation 11.7% Bettge and colleagues conducted a study published in Diabetes, Obesity, and Metabolism in 2017 that showed that individuals who were taking metformin while taking a GLP-1 were more likely to have side effects, especially nausea and vomiting
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