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Patients should seek urgent medical attention if they develop: Severe symptoms including extensive vulval swelling or ulceration Systemic features such as fever Pregnancy with severe symptoms Immunocompromised state with infection Unusual vaginal discharge with offensive odour, particularly if accompanied by pelvic pain, which suggests possible pelvic inflammatory disease requiring prompt antibiotic therapy Any vaginal bleeding outside normal menstruation It is important to note that over-the-counter fluconazole has specific licensing restrictions and may not be available without prescription for all patients
More serious but rarer side effects include pancreatitis (uncertain risk increase), gallbladder disease (increased risk with rapid weight loss), hypoglycemia when combined with other diabetes medications, and injection site reactions
DOI: 10.1080/14656566.2024.2343092
Higher-exposure protocol design: Advanced daily totals demand tighter monitoring and cleaner execution
Why is combining GLP-1 medications with lifestyle changes important for lasting weight loss
