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Roger L, Tomas F, Gire V

Antitumor action of curcumin in human papillomavirus associated cells involves downregulation of viral oncogenes, prevention of NFkB and AP-1 translocation, and modulation of apoptosis

It is distinct from hydroxocobalamin (covered by J3425) and from methylcobalamin, which has no standalone J-code and would require J3490 (unclassified drug) with an invoice

Loading For deficiency without neurological features, the standard loading regimen is hydroxocobalamin 1mg intramuscularly three times a week for two weeks, six injections in total

Each format has tradeoffs that map onto where the user is in the staged titration protocol