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Whether it persists at real-world doses and durations is not verified in controlled human data
For example, semaglutide slows gastric emptying, which is therapeutically beneficial for blood glucose control and satiety but can have implications if you require surgery or certain diagnostic procedures
If you are already at the maximum dose, other strategies including medication switches or adjunctive therapies become the focus
However, in the last month, following the CVS formulary change, this trajectory shifted again
In this review, we present the efficacy and safety data for the pipeline of obesity pharmacotherapies with a focus on entero-pancreatic hormone-based treatments and we consider the clinical implications and challenges that the new era in obesity management may bring
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