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NCT04255433) is expected to provide definitive answers on the impact of tirzepatide on cardiovascular disease compared with dulaglutide, a long-acting GLP-1 RA that has been shown to be cardioprotective in individuals with type 2 diabetes at increased cardiovascular risk [31]
As no medications are available to treat G6PD deficiency, here we seek to identify a small molecule that corrects it
Depending on the polar hydrophilic ligand selected, one or more functional groups on the polar hydrophilic ligand may or may not need to be protected prior to coupling the ligand with the stimulant
The first GLP-1RAs Exenatide synthesized by exendin-4 was approved by the FDA in 2005 (Mariam and Niazi, 2024)
