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Make sure you're not injecting on an empty stomach if this bothers you
The drugs peripheral pathway of appetite control involves mechanisms outside of the central nervous system, such as boosting insulin levels in the pancreas
When symptoms persist for more than a few weeks, medical evaluation for gastroparesis is essential and of utmost importance
GI side effects nausea, vomiting, constipation, diarrhea are the primary tolerability concerns and are managed through careful dose titration
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![Physiologic effects of GLP-1 (adapted from Granata et al. [11])](https://www.researchgate.net/publication/359199250/figure/fig1/AS:11431281081130351@1661532031197/Physiologic-effects-of-GLP-1-adapted-from-Granata-et-al-11.png)
