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Clinicians prescribing these antidiabetes agents, particularly for patients with coexisting cardiac or renal risk factors, may have an additional consideration a potential neuroprotective effect against Alzheimers disease, says Feixiong Cheng, PhD, Director of Cleveland Clinics Genome Center and one of the studys corresponding authors

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The lack of an endogenous equivalent of the HaloTag protein in mammalian cells minimizes the chances of detecting false positives or nonspecific interactions