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However, conjugation of drugs may not always be necessary
Individual health history, current medications, and aesthetic goals all inform the best approach
doi: 10.1212/01.wnl.0000238163.71349.78 24 ElahyM.JackamanC.MamoJ
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In the CNS, laminin deficiency leads to BBB breakdown, characterized by reduced pericyte coverage, leukocyte extravasation, and altered expressions of VE-cadherin, claudin-5, and occludin, underscoring laminin's role in maintaining BBB integrity [51, 66,67,68]
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