This mechanism would bypass the gastrointestinal tract and provide steady-state drug levels over an extended period
Both MT-I and MT-II activate the MC1R receptor on melanocytes the skin cells that produce melanin pigment
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Declarations Authors contributions Designed the paper, selected and prepared the references, prepared the figures, wrote the manuscript: Wright JW Prepared the references, wrote the manuscript: Harding JW Availability of data and materials Not applicable
Metformin, the first-line oral glucose-lowering agent recommended by NICE for type 2 diabetes (NG28), is well established as a cause of B12 malabsorption