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From a pharmacological perspective, many of these effects are exposure-dependent, supporting the concept that treatment response may vary across dose levels

[Effect of hCG on adrenal cortex activity and on metabolism of desoxycorticosterone] [PMID: 13071825] Laboratory literature summary: [Effect of hCG on adrenal cortex activity and on metabolism of desoxycorticosterone]

Dose, rate of weight loss, baseline BMI, and individual reproductive hormone baseline all influence outcomes

10.1164/rccm.200811-1730OC

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