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By activating both receptors, Zepbound helps reduce body weight by decreasing food intake and enhancing insulin sensitivity

10.1016/j.xcrm.2021.100471 70 HuangQ.LiD.WeiX.JiaY.ZhangZ.AiB.et al (2019)

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PGC-1 is a master regulator of mitochondrial biogenesis and interacts with AR and other steroid receptors to modulate gene expression in skeletal muscle

While semaglutide is known to improve these metabolic parametersdata not captured in our studyour results suggest that in women with established infertility, these physiological benefits may not directly translate into improved clinical pregnancy or live birth rates, highlighting a distinction between spontaneous conception and fertility-related care