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These effects are typically mild to moderate in severity and often diminish over time as the body adjusts to the medication

History of cirrhosis was also a significant predictor of HE, GIB, AKI, HRS, and infection

This metabolic shift rapidly depletes cellular glycogen reserves, generates excessive lactic acid, and leads to the crushing, unyielding fatigue that characterizes the Long COVID experience

2016 Oct;17(10):970-6

doi: 10.3389/fcvm.2026.1735431 Received 31 October 2025 Revised 07 February 2026 Accepted 27 February 2026 Published 27 March 2026 Volume 13 - 2026 Edited by Wanlu Ma, Japan Friendship Hospital, China Reviewed by Pei Wang, University of Washington, United States Asterios Deligiannis, Aristotle University of Thessaloniki, Greece Updates Copyright 2026 Sun, Yang, Xu and Liu