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Here's what the science says and what it means for your protocol

Research published in Frontiers in Immunology demonstrated that these patients show reduced microbial diversity, decreased populations of beneficial bacteria (including Lactobacillus and Bifidobacterium species), and increased intestinal permeability, commonly known as leaky gut

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Ethics declarations Ethics approval and consent to participate Approval for this study was obtained from the ethics committee of the French Society of Intensive Care (protocol number, FICS20020231)

Updated timeline: May 2026: TRIUMPH-1 Phase 3 topline results announced Late 20262027: Remaining TRIUMPH trials complete