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The treatment for 24 weeks led to substantial reductions in liver fat content across all dosage levels, with a mean relative change from baseline of up to -82.4% for the highest dose
[10] [11] Phase 2 trial data published in the New England Journal of Medicine in 2023 (Jastreboff et al.) demonstrated substantial effects on body weight and metabolic parameters, though the full benefitrisk profile is still being established in ongoing Phase 3 trials
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