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Notably, addition of BHB was able to increase the numbers and functionality of cultured human CD4 + T cells, even in the absence of amino acids (Fig

Mechanistically, GLP-1RAs suppress neuroinflammation by shifting microglia from a pro-inflammatory to a phagocytic, anti-inflammatory phenotype

Van Eck, M

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Therefore, the inhibitors developed for the C467 residue of ASCT2 boast the advantages of high specificity and high potency, which can effectively avoid the loss of competitive inhibition by substrate analog inhibitors due to high substrate concentration