Referenced Citations Safarinejad, M.R
Merck and others are developing GLP-1s (MK-8521, orforglipron licensing, etc.), but as of 2026 none have announced capacity builds because their products are not yet commercial
Providing a treatment option that is proven to lower this cardiovascular risk is a major advance for public health. The FDAs decision is largely based on data from the SELECT trial, which included more than 17,000 overweight or obese patients with a baseline age of 45 years old
In addition to its potential influence on sleep patterns, DSIP appears to influence levels of corticotropin, inhibit the production of somatostatin, reduce stress hormone secretion, maintain normal blood pressure, alter sleep patterns and also may impact pain perception
doi: 10.1038/sj.bjp.0707462 51 JenhCHCoxMACuiLReichEPSullivanLChenSCet al