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[33] Homocitrate is enzymatically dehydrated by homoaconitase (HAc) (E.C 4.2.1.36) to yield cis -homoaconitate
B12 is naturally found in animal products, such as meat, poultry, fish, dairy, and eggs
Nonetheless, due to biological and physiological differences between a small animal model and humans, such as a thinner cartilage, possible spontaneous healing of defects, biomechanics, and physical loading in small animals, thus, an additional chondral defect repair study using minipigs should be conducted to confirm these effects
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Em termos prticos, a via oral favorece uma exposio local sustentada do trato digestivo, enquanto a injeo favorece picos sistmicos mais altos e mais bem direcionados a tecidos perifricos
