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Research has observed stimulation of follicle size and elongation, as well as modulation of hair growth cycle signalling

Headaches, nausea, kidney stones, asthma attacks in individuals with asthma, abdominal pain, chest tightness, and even kidney failure have also been reported as possible side effects

The mechanism appears to involve both an anti-inflammatory effect on melanocytes and normalization of the barrier function

Evidence for a free radical mechanis

In addition, menstrual reflux to the ovary and repeated bleeding in local lesions of the ovary may also lead to an iron-overloaded environment in follicular fluid