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El GLP-1R se encuentra en mltiples tejidos perifricos como pncreas, intestino, rin, tejido mamario, pulmn, corazn y cerebro 19,20 , mediando la activacin de la protena cinasa A (PKA) o del factor intercambiador de nucletidos de guanina regulador por AMPc (EPAC) (Figura 2) 21
For most people, GLP-1 side effects are not dangerous
If it has not kicked in yet, that does not always mean it is weak
Therefore, the goal is not simply short-term weight reduction, but a provider-guided plan that supports safer decision-making over time
Safety and long term effects also need further evaluation
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