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The most likely cause of the renal changes seen after maternal exposure is the inability of the developing fetal kidney to handle the increased urinary volume caused by the SGLT2 inhibitor (71)
Food preparation methods that utilize high heat, such as frying, grilling, and broiling, lead to the formation of more AGEs, while cooking at lower temperatures, shorter cooking times, steaming, boiling, and the use of acids like lemon juice or vinegar in cooking minimize AGE formation (Uribarri 2010)
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