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Pickart estimated the toxic dose at approximately 22,500 mg, which is over 11,000 times the recommended daily dose
Synaptic functionality of these synapses was demonstrated via the presence of analog-induced spinogenesis, and the colocalization of synaptic markers in newly formed dendritic spines which were coupled with enhanced miniature excitatory postsynaptic currents
Further, well-designed clinical studies are needed to confirm the efficacy and safety of both peptides in clinical practice
It is strictly for research purposes only, and human safety is not established
Nuclei were stained with 5 g/mL DAPI
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