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Impact of socioeconomic position on initiation of SGLT-2 inhibitors or GLP-1 receptor agonists in patients with type 2 diabetes a Danish nationwide observational study
This initiative is timely: the global market for GLP-1 obesity and diabetes drugs is exploding (projected ~USD 62 billion in 2025 to ~USD 157 billion by 2035 ( [7] ), with forecasts of ~$200 billion by 2030 ( [8] ) and tens of millions of patients on GLP-1s by the end of the decade)
For example, in a study where obese volunteers had unlimited access ( ad libitum ) to three meals (lunch, dinner and snacks), it was observed that treatment with semaglutide (1 mg/wk) caused a 24% decrease in energy intake during the day, leading to a reduction in body weight of approximately 5 kg after 12 weeks of treatment
These findings suggest that reduced degradation of the N-terminal leads to an improvement in metabolic stability [2]
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