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It is constantly used by our body cells to keep them functioning properly and protect them from damage due to free radicals

The aim of the present narrative review is to provide an integrative synthesis centered on melatonin, examining how its age-related decline mechanistically connects circadian disruption, sleep impairment, chrononutritional factors, and antioxidant defenses

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Some suggest a 3-hour gap to maximize individual absorption, but for most people, the convenience of taking them together outweighs any minor benefit of spacing them out