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The current global prevalence of inborn errors of metabolism is approximately 1 in 2000 people, with 2030% of individuals experiencing epilepsy as their primary neurological manifestation [2]
The study further highlighted glutathiones role in supporting important immune cells, including Th1 lymphocytes and macrophages, which help protect the body against bacteria and viruses
This binding triggers an inflammatory response, activating nuclear factor-kappa B (NF-B) and mitogen-activated protein kinases (MAPKs), leading to the production of pro-inflammatory cytokines such as TNF- , IL-1, and IL-6 (55)
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The SMN complex has been well established to act in the cytoplasm as a chaperone-catalysing assembly of snRNPs, essential components of the spliceosome 18
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