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This does not mean the medications are unsafe

Makes fasting easier

This shows that staying hydrated is very important

The recommended dosages are based on the data from clinical trials for that specific use. For both types, higher doses may lead to negative side effects Increasing the dosage for both types of medications can come with negative side effects (nausea, vomiting, constipation, fatigue, loss of appetite and more)

[2] Whilst multiple mechanisms likely contribute to these benefits, including improved glycaemic control, weight loss, and blood pressure reduction, changes in vascular inflammation may play a role