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Placenta (2018) 69:15361
Are tirzepatide plateaus different for everyone
Typical titration Start: 2.5 mg once weekly for 4 weeks (a starter dose to help your body adjust) Increase to: 5 mg once weekly Then, if needed and tolerated, increase by 2.5 mg every 4 weeks to 7.5 mg, 10 mg, 12.5 mg, and up to 15 mg once weekly Your prescriber will tailor the dose based on blood sugar targets (for Mounjaro), weight response (for Zepbound), and side effects
Some people do stop without tapering, but a gradual reduction is often discussed as more manageable
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