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GLP-1 receptor agonists are the obvious current example
Endocannabinoids in amygdala and nucleus accumbens mediate social play reward in adolescent rats
It suffers from bioavailability issues, and the CNS-targeting theory remains unvalidated for this specific compound
However, individuals with rare genetic conditions like Lebers hereditary optic neuropathy or those with known severe hypersensitivities to cobalt should avoid these shots
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