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Sestrin2 has been reported to protect insulin-resistant cells by activating the AMPK pathway or upregulating the mTOR pathway (Tian et al., 2022)
However, the chemical composition of GSH does not allow it to be taken orally for central nervous system diseases because little to none crosses the blood-brain barrier
Amino acids make up 75% of the human body
2006 Apr 5;54(7):2479-83
Wang W, Wang W, Pan Y, Tan C, Li H, Chen Y et al (2022) A new gain-of-function OsGS2/GRF4 allele generated by CRISPR/Cas9 genome editing increases rice grain size and yield
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