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The CANTOS (Canakinumab Anti-inflammatory Thrombosis Outcomes Study) demonstrated that anti-inflammatory therapy reduced the incidence of MACEs by 15% in atherosclerosis patients without affecting lipid levels
Los autores de un metaanlisis de 2013 combinaron los resultados de este estudio con los de 12 estudios ms pequeos [49]
Cagrilintide, with six amino acid substitutions in human amylin and a dual carboxylic fatty acid chain similar to semaglutide attached to the first amino acid, lysine, exhibits an extended half-life, allowing for a once-weekly subcutaneous administration regimen [97,98]
Drug: GZR18 GZR18, developed by Gan and Lee Pharmaceuticals, USA, is currently undergoing a Phase II trial to assess its efficacy and safety for weight management in obese or overweight individuals
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