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it remains an investigational compound in clinical development
Conversely, in patients with anorexia nervosa, even supra-physiologic GH doses (mean maximum daily dose: 1.4 mg/day) may not be sufficient to normalize IGF-I levels (61) indicating the important role of hepatic GH sensitivity in successful IGF-I generation
recommended daily allowance (RDA) is: 2.4 micrograms (mcg) per day Certain groups may require higher intake, including: Pregnant women: 2.6 mcg daily Breastfeeding women: 2.8 mcg daily Older adults Vegetarians and vegans Individuals with absorption issues 500 mcg to 5000 mcg , which is significantly higher than the RDA but still generally considered safe when medically supervised
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