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Your brain normally tracks fatigue through a molecule called adenosine, which accumulates the longer youre awake and docks onto specific receptors to signal slow down. Caffeines molecular shape is close enough to adenosines that it physically occupies those same receptor sites (A and AA receptors, specifically) without triggering the slow down signal

To view a copy of this licence, visit About this article Cite this article Ozler, E., Sanlier, N

That result sparked a near-5% increase in Roche's share price, and the latest announcement had a similar effect, with the stock up just over 5% at the time of writing

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