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Other Outcomes At week 104, among patients receiving semaglutide, the mean systolic blood pressure decreased from 135.6 mm Hg at baseline to 132.2 mm Hg among those receiving 0.5 mg and to 130.3 mm Hg among those receiving 1.0 mg, for reductions of 3.4 mm Hg and 5.4 mm Hg, respectively
It effectively suppresses pro-inflammatory mediators, such as nitric oxide (NO), IL-6, TNF-, IL-1, and IL-8, as reported in macrophages stimulated by lipopolysaccharides (LPS) and human dental pulp cells exposed to inflammatory stimuli
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