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The recommended values of eGFR and ACR for use of dapagliflozin in people without type 2 diabetes relate to the parameters of the population enrolled in the DAPA-CKD trial
A good metric to consider is this: If an obese patient (BMI 30 to 34.9) is on a GLP-1 for six months and has not reached 10% TBWL, they should be referred back to their primary care provider to reassess their weight-loss plan
The price gap is real, but it reflects the cost of manufacturing standards, testing, medical oversight, and regulatory compliance
Cisplatin in cancer therapy: Molecular mechanisms of action
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