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L-type calcium channel-mediated zinc wave is involved in the regulation of IL-6 by stimulating non-IgE with LPS and IL-33 in mast cells and dendritic cells

Branca JJV, Maresca M, Morucci G, Becatti M, Paternostro F, Gulisano M, et al

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This intervention influenced energy dissipation and insulin sensitivity through AMPK pathway activation, underscoring MOTS-c's potential as a subject of research into menopause-induced metabolic dysfunction

Most trials are still ongoing and only one prospective randomized clinical trial with a primary outcome of major cardiovascular events in patients with T2D has reported its results [28]