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Injectable semaglutide 2.4 mg (Wegovy) produces somewhat greater weight loss than orforglipron: approximately 14.9% at 68 weeks in the STEP 1 trial versus 11.2% at 72 weeks with orforglipron 36 mg in ATTAIN-1
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Originally approved for diabetes, GLP-1 drugs are positively used in the management of weight loss, cardiovascular risk, fatty liver disease, and neurodegenerative conditions
Sexual and appetite effects can show up faster but vary widely from person to person
Ions were introduced to the mass spectrometer using an Easy-Spray source operating at 2 kV
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