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Gentle, supportive measures removing the source, improving diet, hydration, fiber and bowel regularity, sleep, antioxidant and mineral status are reasonable for people with low-level exposure, vague or mild symptoms, and no evidence of significant poisoning

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When tumours reached ~100 mm 3 on average per genotype, animals were randomized by ranked allocation across all groups and given 5FU (10 mg kg 1 ), metformin (250 mg kg 1 ) or vehicle (PBS) daily by i.p

GA, Hillier TA, Brown JB