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This study suggests that GLP-1 can enhance the function of brown fat, increase heat production in BAT, and reduce body weight in mice by modulating the activity of the sympathetic system through binding with GLP-1R in the center

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But remember, this is a temporary measure

Creatine has been shown to reduce muscle fatigue by increasing muscle energy during exercise (Smith-Ryan et al., 2021)

Experimental observations in these models include changes in circulating metabolic markers, altered hepatic lipid accumulation, and modulation of gene expression related to energy metabolism pathways