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Key expectations for long-term treatment include: Weight loss velocity decreases over time, with most reduction occurring in the first 912 months Plateaus lasting 48 weeks are common and do not indicate treatment failure Individual response varies based on genetics, baseline metabolic health, adherence, and lifestyle factors Continued medication use is typically necessary to maintain weight loss Non-scale victoriesimproved mobility, reduced medication burden for comorbidities, better quality of lifeare equally important outcomes Patients should also be aware of potential adverse effects that may affect long-term adherence
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These gastrointestinal effects are generally mild to moderate and far less dangerous than the complications of uncontrolled diabetes, such as heart disease, kidney damage, and nerve damage
GHSR agonists (Ipamorelin) activate the ghrelin receptor pathway
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