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Item etal, 2004), and reduced production of CoQ10, both of which would lead to poor muscle tone

Patients often report feeling less irritable or anxious, and even finding relief from symptoms of depression linked to their deficiency

However, these do have to be prescribed and administered by a healthcare professional, and are more likely to be given to people who have lifelong conditions affecting their ability to absorb B12 or who are at higher risk of consistent deficiency

The dosage is based on medical condition, response to the treatment, age, and weight

A 2016 study noted its impact on reducing gut inflammation and protecting against ulcers