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The trend may also be amplified by the visibility of post-weight-loss skin changes, which can be more prominent in certain demographics or individuals with pre-existing skin laxity

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Folic acid (FA)-induced AKI is one of the typical models simulating drug or toxicant-induced tubular injury, which is closely related to crystal formation in the tubule lumen and cellular oxidative stress, leading to massive inflammatory reaction and eventually tubular cell death (Martin-Sanchez et al., 2018)

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