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Sclerostin, encoded by the SOST gene, is secreted by osteocytes and suppresses bone formation
In a statement published alongside the results, Amgen said: Weight loss had not plateaued by 52 weeks, indicating the potential for further weight reduction. It added that improvements were recorded across other cardiometabolic measures, including waist circumference, blood pressure, high-sensitivity C-reactive protein (hs-CRP) and select lipid parameters
The absorbance was measured at 490 nm
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