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Other studies focused on the changes in DPP4 + and ICAM1 + ASCs during obesity [26, 27], and the high stemness of DPP4 + ASCs and their contribution to adipogenesis during high fat diet-induced obesity, which was confirmed in Dpp4 CreER mice [28]

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Nevertheless, this conclusion is hindered by a number of limitations, especially related to the retrospective design of most studies included in the analysis, as well as great variations in the amount and duration of garlic intakes

Its efficacy as a standalone therapeutic agent in human subjects requires further large-scale, double-blind clinical trials

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